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Traditionally, intravitreal administration has been the preferred method for delivering treatments for age-related macular degeneration and DR, but this approach has been accompanied by side effects, such as increased intraocular pressure and intraocular hemorrhage, necessitating the search for effective and less invasive methods (11)

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Despite remarkable advances in nanomedicine, concerns regarding nanomaterial-induced neurotoxicity have emerged as a significant safety issue

Science 179: 588-590.Google Scholar ROVERI, A., MAIORINO, M., NISII, C