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Each CBS monomer has a modular structure: An N-terminal heme-binding domain is directly followed by a highly conserved catalytic domain of 311 amino acids (aa) in length, which contains the binding site for PLP, including lysine 119, which forms a covalent bond with the ligand

9.3 Effects of endogenous acetaldehyde 9.3.1 Effects of ethanol possibly attributable to acetaldehyde or acetaldehyde metabolism There is no direct evidence to link acetaldehyde with liver injury

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Structural and modelling studies focusing on proton transfer