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Ninety-eight of 114 Depakote ER-treated patients (86%) and 100 of 110 placebo-treated patients (91%) treated at least two weeks maintained the 1000 mg once daily dose for the duration of their treatment periods

Arch Anim Nutr 2003;57(2):127-136

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It thus acts as a buffer by inhibiting lactic acid buildup in muscles, helping to delay fatigue and prevent Tying Up