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A loss of muscle fibers diversity results in monotonous PAS staining with low intensity of staining was found in control rats on the 42nd day, compared to BPC 157 treated rats in which diversity of muscle fibers remained (Figure 14)

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Retatrutide : This triple agonist (GLP-1 + GIP + glucagon) produced 28.7% weight loss in Phase 3 but introduced a new safety signal: dysesthesia (abnormal skin sensations) in 4.4 to 20.9% of participants at the 12 mg dose depending on trial population