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Description
Stimulation leads to rapid phosphorylation of IB, thereby marking it for ubiquitinylation and ultimately proteolytic degradation
Non-targeting siRNA was used as a negative control
The device uses a micro-needle that is half the size of normal injection
The same mechanism applies to Beckwith-Wiedemann syndrome, which is associated with overgrowth, malformations and predisposition to tumors [8, 58]
