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Moreover, in animals, NNMT knockdown improves insulin sensitivity, overnight fasting glucose levels, and glucose tolerance and reduces the relative fat mass [11, 14]

Forelimb grip strength was chosen to measure muscle function since it has been repeatedly shown that C57BL/6 mouse forelimb grip strength begins to decline at or before 24 months of age 18,19,20

People aiming to improve energy efficiency, insulin sensitivity, and metabolic flexibility
