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However, the regulatory effect of these ncRNAs in CHDs needs further investigation

On the other hand GPx3 is negatively correlated with MAPK oncogenic signaling pathway (94), which suggests a potential antitumor effect in thyroid cancer, while a decrease in GPx3 levels predisposes to an increase in the size of primary tumors and the number of metastatic lymph nodes (95, 96)

Of note, C1-27 inhibited the clonogenic survival of HCT116 cells at sub-micromolar concentrations (Fig
