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For example, in SDH-deficient tumors, which rely heavily on glycolysis due to TCA cycle impairment, WZB117, a GLUT1 inhibitor, can effectively reduce glucose uptake, decrease intracellular ATP, downregulate glycolytic enzymes, and inhibit tumor growth, making it a promising candidate for enhancing treatment outcomes and sensitizing tumors to other therapies [35]

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[DOI] [Google Scholar] 55.Bajoria P.S., Dave P.A., Rohit R.K., Tibrewal C., Modi N.S., Gandhi S.K., Patel P

Identification of the absorbed components and metabolites in rat plasma after oral administration of Rhizoma Chuanxiong decoction by HPLC-ESI-MS/MS