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Description
Ninjurin1 increases p21 expression and induces cellular senescence in human hepatoma cells

Dihydrolipoic acid maintains ubiquinone in the antioxidant active form by two-electron reduction of ubiquinone and one-electron reduction of ubisemiquinone

Because they are dissolved in water, any excess of the water-soluble vitamins is excreted through urine and are not stored in the body

Similarly, intestinal Zip8 KO mice exhibit systemic Mn deficiency and aggravated colitis, which can be rescued by inhibition of the downstream sphingolipid enzyme ACER1 (Choi et al., 2024b)
