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Eur J Med Chem 164:654664

Another NAM analog-based NNMT inhibitor, 6-methoxy NAM (also known as JBSNF000088), has shown promise in decreasing body weight and enhancing insulin sensitivity in mice models of obesity induced by a high-fat diet 198

However, we still need to overcome the following several challenges: (1) The active substances still need to be revealed in depth, and the Q-marker should be oriented towards biological effects

Malas, M
