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Appropriate treatment should most importantly first include staging and careful planning of the surgery (Ladlow, 2013), because aggressive, radical excision is crucial to avoid tumour recurrence

Although megaloblastic anemia is the most common hematologic abnormality, vitamin B12 deficiency can potentially affect all bone marrow cell lineages, resulting in pancytopenia[6]

The deficiency of vitamin B12 is defined as a plasma vitamin B12 level of less than 200 pg/ml
