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Some people may also feel like their entire body is swollen, notes MedlinePlus

267 Moreover, the ER-targeting spherical nano-scale particle, self-assembled from endoplasmic reticulum targeting groups with fluorescent labels, endoplasmic reticulum stress inducers, and nuclear DNA-damaging drugs, can also specifically localize to the endoplasmic reticulum and induce endoplasmic reticulum stress, thereby leading to tumor cell apoptosis

These data indicate that the pathologic disruption of dopamine regulation, possibly through alterations in prolactin release, could dysregulate osteoblast and osteoclast function and influence bone resorption and mineralization

However, while the cellular uptake of ERG does require plasma membrane expression, the latest version of the protein atlas indicates mitochondrial expression as well (191)