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The trial was discontinued for reasons that were never publicly specified

If the ODT works for you at 5 mg but you would benefit from 7.5 mg or more, you have no oral option for escalation and would need to switch to injection

The ability of CRISPR-Cas9 to specifically inactivate target genes on the bacterial chromosome has been demonstrated in the cases of Staphylococcus aureus [222,223], Clostridioides difficile [224,225], and Klebsiella pneumoniae [226] (Table 4 and Table 5)