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45 In hereditary elliptocytosis, the membrane fails to rebound from deformation, and RBCs progressively elongate to form visible elliptocytes, which causes a mild to severe hemolytic anemia

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To confirm that the diet-induced changes in CDO half-life observed in whole animals are due to regulation of CDO ubiquitination and degradation by the 26S proteasome, we explored CDO ubiquitination in response to diet in intact rats (Dominy et al

Andrew: Yes, it makes things other than melatonin
