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Almaguer-Mederos, L

[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Nahlkov J
Clinical Biochemistry

The flexibility of this signaling pathway and multiple regulatory mechanisms make necroptosis potentially bidirectional in tumor microenvironment remodeling, chemotherapeutic resistance and immune escape, namely, it can exert both antitumor and pro-tumor effects depending on the context (131)