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Interference with JAK-STAT signaling in known not to affect the viability of senescent cells(Xu et al., 2015) and we have previously observed similar effects for NFB and p53 inhibition(Freund et al., 2011
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Approach Short trial arm Duration 12 weeks Review Point Week 12 Notes METAOD005 used 12 weeks at oral doses 1-30 mg/day in 300 obese adults
The idea now is people are being forced to go back too quickly in countries like in Scandinavia perhaps, where they get more time
