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Daily Administration Schedule: Morning option : 30-60 minutes after waking (on empty stomach) Evening option : 1-2 hours before bed (preferred by most researchers) Consistent timing : Same time daily throughout the active cycle The subcutaneous injection method proves most common, with rotation between injection sites recommended to prevent tissue irritation

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Earlier framings of "0.34 partial agonist at GCGR" or "0.4 softened agonist at GLP-1R" mistook potency ratios (EC50_LY EC50_native) for efficacy multipliers (E_max_LY E_max_native) and are retracted

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