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In ZDHHC11 knockdown cells, we observed that the levels of p62 protein rather than p62 mRNA was significantly reduced, which could be prevented by the lysosomal inhibitor chloroquine (Figs
Moreover, most studies highlight the potential risks and dangers of coffee enemas
Sources: Brody, B
As the exact mechanism of POCD and POD remains to be explored, the activation of inflammation and immune systems is strongly regarded as the key mechanism for cognitive deterioration in postoperative period 6
