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Usuki F, Yamashita A, Kashima I, Higuchi I, Osame M, Ohno S
In addition, sUA mediates the IRS2 protein degradation pathway and activates AMPK/mTOR in macrophages, which reduces macrophage energy consumption leading to IR (60)
This helps to avoid excessive drops in blood sugar levels
In addition, we design special functionalized linkers supporting cysteine disulfide cross-linking and multi-site cross-linking, meeting application requirements across ADCs, protein drugs, nucleic acid drugs, and other fields
