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Loria CM, et al

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218 In addition, a general feature of proteinaceous membrane-less organelles (PMLOs), such as Cajal bodies, nuclear speckles, and stress bodies, appears to be their large-scale inclusion of IDPs, which may contain properties favorable for PMLO biogenesis, including intrinsic flexibility and low-affinity interactions

This metabolic process is closely linked to inflamation, aging and neurodegenerative disorders
