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Description
By selectively blocking NNMT, 5-Amino-1MQ is investigated for its ability to preserve cellular NAD+ pools, reduce methylation of nicotinamide to inactive 1-methylnicotinamide (1-MNA), and enhance sirtuin activity and energy metabolism
It plays a key role in stimulating the release of gonadotropin-releasing hormone (GnRH), which is essential for puberty onset and maintaining reproductive function
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Epub 2021 Apr 30
