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As cancer cells contain high amounts of Cu through the trans-membrane Cu transporter Ctr1 transportation, DSF can form a complex with Cu, enabling it to penetrate into cancer cells
doi: 10.1016/s0891-5849(02)01040-7
Editorial: Impact of Lipid Peroxidation on the Physiology and Pathophysiology of Cell Membranes
The denominator is further refined as the number of patients confirmed with severe sepsis or septic shock through medical record review for the presence of a suspected infection, two or more SIRS criteria, and a sign of organ dysfunction that are all documented within 6 hours of each other
