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Description
Deficiency in microglial autophagy promotes profound dysfunction at behavioral, cellular, and molecular levels
Network Research Center for Liver and Digestive Diseases (CIBEREHD), Madrid, Spain
PLoS Pathog (2011) 7:e1002250.10.1371/journal.ppat.1002250 42 SalzanoSChecconiPHanschmannEMLilligCHBowlerLDChanPet alLinkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal
However, corticosteroids can also increase oxidative stress, which may in turn reduce corticosteroid sensitivity in patients by several mechanisms
