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2nd edition McIlwain CC, Townsend DM, Tew KD (2006) Glutathione S -transferase polymorphisms: cancer incidence and therapy

Key Takeaway: Wellness is a marathon, not a sprint

doi: 10.1007/s00787-022-02047-x 220 LiMFallinMDRileyALandaRWalkerSOSilversteinMet al

Receptor autophosphorylation, downstream phosphorylation of IRS-1 and Shc, and activation of PI3K and MAPK occur with similar kinetics to native IGF-1 once the ligand reaches the receptor
