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When it comes to supplements, taking high doses of vitamin C at the same time as your B12 shot might slightly lower the amount of B12 your body can use, but this is more relevant for oral B12 supplements than injections
[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Zamyatnin AA
This is when the adrenals are so exhausted that they are unable to adapt to stress
