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Therefore, with their action of the GABAergic system, and their involvement in arousal, cognition, emotion, and motivation, neurosteroids may hold therapeutic potential in treating AUD (Zorumski et al., 2013

doi: 10.1038/s41577-024-01112-7 136 PhanATGoldrathAWGlassCK

: A Phase I New Approaches to Neuroblastoma Therapy Study of Buthionine Sulfoximine and Melphalan With Autologous Stem Cells for Recurrent/Refractory High-Risk Neuroblastoma

At the molecular level, S6K1 enhances the efficiency of MYC translation by regulating phosphorylation of the eukaryotic initiation factor eIF4B
