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While each approach has demonstrated promise in preclinical and early clinical studies, resistance mechanisms, off-target effects, and intratumoral heterogeneity continue to limit their widespread clinical success

Quantification of undifferentiated markers Feeder cells were seeded with 1.25 10 4 cells/well in a 96-well plate and cultured for 1 day, and iPS cells were additionally seeded with 5000 cells/well and cultured for 1 day

This is also seen in humans, leading to the recommendation that EDTA chelation be followed by a short course of DMSA [115]

10.1523/JNEUROSCI.3986-07.2007 104 TranT
