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Gotteland et al
Most chronic wounds are characterized by a prolonged or excessive inflammatory phase, marked by an overabundant infiltration of neutrophils, persistent infections, frequent formation of atypical tissue and organ biofilms, and the inability of dermal or epidermal cells to respond to reparative stimuli
The remaining cartilaginous portions of the epiphyses become thinner
First, BPC-157 upregulates growth hormone receptor expression in tendon fibroblasts (Chang et al., 2014), thereby sensitizing the cells to circulating growth hormone and amplifying local repair signalling
