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Bollong MJ, Lee G, Coukos JS, et al
The -thiopropionate linker exhibits enhanced plasma stability owing to its sterically hindered configuration, while facilitating swift cleavage through intramolecular cyclization in moderately acidic environments (pH 4.55.5) commonly present in phagosomes and endosomes ( Mycobacterium tuberculosis and Leishmania species, which inhabit acidified phagosomal compartments
J.FilippovaA.LingS
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