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Isotretinoin was shown to downregulate TLR-2 expression and further regulate TLR-2-mediated abnormal innate immune responses in rosacea [144]
CheongIDeelchandDKEberlyLEMarjanskaMManousakisGGulianiGet al
There are also numerous other compounds found in a full-spectrum [BSO], including sterols and saponins, novel lipid constituents, and volatile oils of varying compositions
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