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It reduced hippocampal cell damage and improved brain tissue metabolism by enhancing the function of the gut-brain axis (63)

The glutathione homeostasis system mainly contains five enzymes, -glutamylcysteine synthetase and glutathione synthetase involved in glutathione biosynthesis, glutathione peroxidase and glutathione reductase involved in recycling of the GSH, and glutathione S-transferase involved in detoxification of several stressors 20,25,27

Similar content being viewed by others Introduction Major depressive disorder (MDD) is a common and serious mood disorder that is thought to affect up to 3.8% of the population worldwide (around 280 million people) (Evaluation, 2021)