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[DOI] [PubMed] [Google Scholar] Becejac T, Cesarec V, Drmic D, et al
Among these, the valine-to-isoleucine substitution (V717I) was one of the first identified mutations, playing a pivotal role in the development of the amyloid cascade hypothesis of AD pathogenesis
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Something to consider when evaluating whether or not to cleave the GST moiety away is that GST is a homodimeric protein
