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Additionally, an increase in CB 2 receptor expression has been positively correlated with an increase of microglial activation ( 2 receptors in microglia of the substantia nigra and a decreased expression of this cannabinoid receptor in tyrosine hydroxylase-positive cells in patients suffering from PD (Garca et al., 2015
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The HGF/c-Met signaling cascade Dihexa activates triggers structural synaptic modifications that remain stable for days to weeks after the initiating compound has cleared from circulation

Handb Clin Neurol 159: 17393 Elsevier Elbaz A, Carcaillon L, Kab S, Moisan F (2016) Epidemiology of Parkinsons disease
