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Generally, iron accumulation induces OS, bringing about the increase of ROS levels and the imbalance of antioxidant balance and infiltrating pro-inflammatory mediators that further amplify cerebral inflammatory responses, which aggravate neuronal damage during reperfusion (Jin et al., 2013

Int J Pediatr Otorhinolaryngol 89:173178 Steyger PS (2021a) Mechanisms of aminoglycoside-and cisplatin-induced ototoxicity

Methanol (80%) leaf extract of Otostegia integrifolia benth (Lamiaceae) lowers blood pressure in rats through interference with calcium conductance
