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Description
In gut models, it steadies the gut-brain link through the vagus nerve and helps the gut lining make protective mucus
YangYWengWPengJHongLYangLToiyamaYet al Fusobacterium nucleatum increases proliferation of colorectal cancer cells and tumor development in mice by activating toll-like receptor 4 signaling to nuclear factor-B, and Up-regulating expression of MicroRNA-21
Subsequent work has reported that the spinogenic effect requires HGF/c-Met activation and is blocked by the same Hinge antagonist that blocks the procognitive effect in vivo [3]
Manolopoulos D
