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Hypothalamicpituitarythyroid axis The process of thyroid hormone synthesis and secretion is regulated by a negative feedback loop and this process depends upon: the hypothalamus - a region of the brain responsible for monitoring messages from the nervous and endocrine systems the pituitary gland - often called the master gland because it controls a number of hormone glands in your body, including the thyroid and adrenals, the ovaries and testes the thyroid gland - butterfly-shaped organ located in the base of your neck

Zheng D, Li J, Yan H, Zhang G, Li W, Chu E, et al

doi: 10.1161/JAHA.123.030676

Current evidence suggests that exercise training improves musculoskeletal robustness and metabolic regulation, while bioactive food components (phytoestrogens, polyphenols, omega-3s) may offer complementary support for inflammation and hormonal balance