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doi: 10.1016/j.bbadis.2011.12.002

The regulatory mechanisms of ferroptosis identified to date include mainly iron metabolism, such as iron transport and ferritinophagy, and redox systems, such as glutathione peroxidase 4 (GPX4)-glutathione (GSH), ferroptosis-suppressor-protein 1 (FSP1)-CoQ 10 , FSP1-vitamin K (VK), dihydroorotate dehydrogenase (DHODH)-CoQ, and GTP cyclohydrolase 1 (GCH1)-tetrahydrobiopterin (BH 4 )

Notably, clinical antibiotic use frequently exacerbates colitis symptoms (84), further underscoring the critical role of microbial homeostasis in maintaining intestinal health

Columbic interactions, hydrogen bonding, and hydrophobic interactions involve in this type of immobilization
