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FDA-approved drugs, Cushman says, have been tested and reviewed not just for their efficacy but also for their safety

Genet., 2003, 40 (4), 290295

Sci Transl Med 2020;12:eaay0167

In the context of T-cell acute lymphoblastic leukemia (T-ALL), nelfinavir has been shown to inhibit the NOTCH1 pathway by blocking -secretase activity through the inhibition of presenilin processing
