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Elevated homocysteine has been associated with skin changes including hyperpigmentation, and some research connects poor methylation status to inflammatory skin conditions
Zhu XJ, Lin YJ, Chen W, Wang YH, Qiu LQ, Cai CX, Xiong Q, Chen F, Chen LH, Zhou Q, Li JH (2016) Physiological Study on Association between Nicotinamide N -Methyltransferase Gene Polymorphisms and Hyperlipidemia
Cardiovascular outcomes during extended follow-up of the AIM-HIGH trial cohort
