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In preclinical data, the pair improves adipocyte NAD+ by inhibiting NNMT, resulting in better fat metabolism and reduced obesity.[8][3] For anti-aging, this translates to improved tissue resilience and reduced senescence

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10.1016/S0015-0282(16)59837-9 92

Future research should actively focus on preclinical evaluations using large animal models, such as pigs, dogs, and non-human primates, systematically assessing the safety, pharmacokinetic characteristics, and therapeutic effects of exosome therapies under more human-like anatomical and physiological conditions