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Description
In addition, tumors treated with PD-1/PD-L1 blocking antibodies develop resistance through upregulation of CD38 induced by all-trans-retinoic acid and IFN in the tumor microenvironment [47]
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5-Amino-1MQ remains the most commonly deployed pharmacological reference tool across this literature because of its active-site selectivity, cellular permeability, and reproducible target engagement signature (1-MNA reduction)
