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[138] first found that GSTZ1 could enhance sorafenib-induced ferroptosis by inhibiting the nuclear factor erythroid 2-related factor 2/glutathione peroxidase 4 (NRF2/GPX4) signaling pathway in hepatocellular carcinoma (HCC) cells

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Clin t average intrinsic clearance verapamil 1 12.5 / 3 4 7-ethoxycoumarin 136.7 7 / was also monitored as high, moderate and low metabolized standards, respectively