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[100], in a systematic review of preclinical and clinical studies in psychosis, concluded that despite variable findings in the literature due to complicating factors such as lifestyle/environment, sex, gender, age, details of methods for processing fecal samples, and medication effects, the research overall supports the hypothesis of an alteration in the gut microbiome in psychosis, compared to healthy controls, and that the gut microbiome changes may precede the appearance of clinical diagnostic symptoms of schizophrenia-spectrum disorders

[DOI] [PubMed] [Google Scholar] 31.Lin Y.-C., Wu C.-Y., Hu C.-H., Pai T.-W., Chen Y.-R., Wang W.-D