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M., Vena, J

doi: 10.3389/fimmu.2020.00111

The results demonstrate that the copper-induced expression of DJ-1 observed in our proteomic analysis is even more pronounced when cells are exposed to copper at levels that probably lead to toxicity, indicating a role of this protein in copper metabolism (Figure 4A)
[225] conducted a 7month treatment with HRW in 3TgAD mice and demonstrated that it prevented synaptic loss and neuronal death, reduced amyloid plaques, hyperphosphorylated tau protein, and neurofibrillary tangles
