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Since the epigenome changes are largely reversible in principle, manipulating epigenetic imprints holds great prospects in improving tissue maintenance, regeneration ability, and, ultimately, extending health span

In contrast to the reversibly hyperoxidized cysteine sulfenylated proteins, irreversibly hyperoxidized sulfonylated cysteine is generally thought to be an impaired dead end product (e.g., inactivated protein) formed through protein aggregation 25

The density assigned as 3 flanking RNA showed considerable variability in its volume and position, indicating structural heterogeneity

In the experiment, ocular hypertension was induced in rats by injecting 2% methylcellulose into the anterior chamber, blocking aqueous humor outflow and raising IOP