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Originally isolated from a protein found in human gastric juice, this peptide has attracted significant attention in preclinical research due to its potential roles in supporting tissue repair and cellular integrity

A novel SHP-1/Grb2-dependent mechanism of negative regulation of cytokine-receptor signaling: contribution of SHP-1 C-terminal tyrosines in cytokine signaling

Additional models: cartilage, endocrine, kidney In cartilage/chondrocyte culture models: FOXO4-DRI reduced the number of senescent chondrocytes significantly, while healthy chondrocytes remained intact