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Description
[6] Cytotoxic Payloads The cytotoxic payload is a critical component of ADCs responsible for exerting cytotoxic effects, necessitating several key requirements: (1) high cytotoxicity, typically with IC50 values at low nanomolar or picomolar levels (Figure 7)
This multi-target mechanism positions it as a promising dietary intervention, in contrast to high-fat diets that exacerbate gut dysfunction (142, 143)

IGF-1 signaling and muscle regeneration: IGF-1 variants
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