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(105) found that FP cell-free supernatant exerts non-butyrate-dependent anti-inflammatory effects by reducing colonic TNF-/IL-12 and increasing serum IL-10

J Agric Food Chem 2009;57:551823
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Beyond toxicity reduction, emerging studies also suggest that TCM may enhance the efficacy of cancer immunotherapy through multi-level immunomodulatory mechanisms, such as remodeling MDSCs phenotype and function, inducing ICD, activating innate immune responses, and modulating the gut microbiotaimmune axis
