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Funding This work was supported by Tropical Medicine and Biology Platform, School of Science and School of Engineering, Monash University Malaysia
In a physiologically normal menstrual cycle, the pulsatile frequency of GnRH undergoes phase-dependent modulation: during the early follicular phase, GnRH pulses occur at intervals of approximately 90100 minutes, favoring FSH-driven follicular recruitment and estrogen synthesis

Superior Sagittal Sinus, Portal, Superior Mesenteric and Caval Vein and Abdominal Aorta Pressure Recording Recordings followed the procedure, described in detail in our previous vascular studies [14,15,16,20,22,23,24], involving deeply anesthetized rats, a cannula (BD Neoflon Cannula, Eysins, Switzerland) connected to a pressure transducer (78534C MONITOR/TERMINAL

Phosphodiesterase-5 Inhibitors As the name suggests, PDE5 inhibitors inhibit the PDE5 enzyme responsible for the breakdown of cGMP
