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Funding This work was supported by Tropical Medicine and Biology Platform, School of Science and School of Engineering, Monash University Malaysia

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In a physiologically normal menstrual cycle, the pulsatile frequency of GnRH undergoes phase-dependent modulation: during the early follicular phase, GnRH pulses occur at intervals of approximately 90100 minutes, favoring FSH-driven follicular recruitment and estrogen synthesis

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Superior Sagittal Sinus, Portal, Superior Mesenteric and Caval Vein and Abdominal Aorta Pressure Recording Recordings followed the procedure, described in detail in our previous vascular studies [14,15,16,20,22,23,24], involving deeply anesthetized rats, a cannula (BD Neoflon Cannula, Eysins, Switzerland) connected to a pressure transducer (78534C MONITOR/TERMINAL

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Phosphodiesterase-5 Inhibitors As the name suggests, PDE5 inhibitors inhibit the PDE5 enzyme responsible for the breakdown of cGMP

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