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After being injected through the tails of ICR (CD-1) mice, the NP showed significant antinociceptive effects which means loperamide was able to be transported across BBB

VOSviewer-based co-citation analysis revealed that Clinical and Experimental Rheumatology, Arthritis Care & Research, Journal of Rheumatology , and Rheumatology International occupied central positions in the network, exhibiting high node density and robust connectivity, underscoring their pivotal roles in disseminating research on this topic (Figure 4A)

The higher mean concentration was presented in milk from Lebanon (Africa), this can be connected with drinking water contamination (Table 4 )

J Am Geriatr Soc 1986;34:800-6
